nodalpoint.org

Hello Sharma,

I welcome your proposal, but if you want people to take an interest it will need to be more specific. What follows are a few general comments:

At the end of the day whoever makes a proposal for a virtual collaboration will need to put a significant amount of effort in to making it "compelling" (i.e. why would a lot of intelligent, busy people, want to spend time working on this project ?).

For example how do you plan to "scan OMIM" ? OMIM is a largely a free text database, so any scanning would need to rely on natural language processing (NLP). Now not to be too cynical of the potential for text mining to be useful in biology, current results suggest there is still along way to go. Even if you do manage to get useful information out of OMIM, you then face the very real problem of heterogeneous data integration: chromatin structure, transcript processing and initiation, transport to cytoplasm, translation of mRNA, stability of mRNA and stability of the protein. All require data from different, highly incompatible, databases. Not to mention the fact that a lot of experimental data is just not available in machine processable formats.