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NCBI Releases New Primer Design Tool

Primer-BLAST combines primer design (using Primer3) and a specificity check with BLAST.


New SciView interview with Dr Roderic Page

After a long hiatus SciView is back with a new interview with Dr Roderic Page from the University of Glasgow. Dr Page is the current Editor in Chief of Syatematic Biology and developer of TreeView(X), the beloved phylogenetic tree visualization software. He was also the editor of the Current Protocols in Bioinformatics.

As usual here is the link.

Enjoy.


Readme for HexiRPA Document - my personal notes to reading papers

Hexi Reading Professional Articles (HexiRPA):

Readme for the docment:

for Each entry, there are 5 sections:Paper Tag (Line 1-2), Read Date (Line 3), PubMed Citation (Line 4-9), MyNotes (Line 10-12) and End Tag (Line 13)
Line 1 : Paper No. --(HI:HexiRRA Idendifier)
Line 2 : Document Name on myPC --(DN: Document Name)
Line 3 : Date read the paper --(DA:Date)
LIne 4 : Citation of PubMed Format (CP: Citation of PubMed)
Line 5 : Title (TI: Title)
LIne 6 : Authors (AU : Author)
Line 7 : Institutes [one or more lines] (IN : INstitutes)
Line 8 : Abstract (AB : ABstract)
Line 9 : PubMed ID (PM : PubMed ID)


A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies, Nat Biotech

The paper described a framework for comparisons across gene expression microarray platforms and laboratories, which including: 1) Affymetrix; 2) Agilent; 3) Applied Biosystems (ABI); 4) Amersham (now GE Healthcare); 5) cDNA arrays provided by the Cepko laboratory (academic cDNA); 6) Compugen (now Sigma-Genosys); 7) Mergen; 8) long oligonuceotide arrays from the Microarray Core facility at Massachusetts General Hospital (MGH long oligo); 9) MWG BioTech (now Ocimum Biosolutions); 10) Operon. As a result, the commercial platform ABI has the best performace, where the academic cDNA from Harvard poorest.


WHY DO PROTIENS HAVE UNWANTED RESIDUES IN THEIR SEQUENCE?

Isoenzymes have similar function but different
structures.

             
This means these protiens have similar active sites. We know that some enzymes
even if their polypeptide chain is shortened can perform their function.
So what's the Use of these "unwanted" amino acids?
                             
Please make me Knowledgable in this scientific query.


Nodalpoint Wiki

Greg is a busy lad just now - I'm sure he won't mind my announcing the new Nodalpoint Wiki. Built using the fabulous DokuWiki, we'd like this to complement the main site by providing a place for collaborative articles, site documentation, coding tips and tricks or whatever you like.

You can login with your Nodal username and password - give it a try and let us know what you think.

Update: The wiki is now fully operational. Previously only admins were able to login and edit pages, this has now been fixed (the problem was due to a bug in the authentication code). Check out the Entrez programming utilities hacks and BLAST hacks. Feel free to contribute.


And so another month is almost gone...

As much a reminder to myself as a spur for the rest of you...

Can it be the end of April already? Where does the time go? More importantly, get thinking about your next submission for "Bioinformatics paper of the month" in 2 days time.


bioinfo.co.nr

Please reveiw my website

src = "http://www.bioinfo.co.nr"


science news feed created

Hi

I've created an RSS newsfeed for my science news webzines (science news RSS). The webzines cover a wide range of scientific topics including chemistry, biology and biomedicine (as well as some bioinformatics and genetics)

Thanks

David Bradley Science News Writer

This item edited to point to the new location of my science newsfeed


genemohan

here is an enthusiastic biotechnolgist trying to make a mark in the field of genomics


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