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AAAI'06: Highlights and conclusions

The AAAI conference finished last Thursday, here are some highlights and papers that might be worth reading if you are interested in building and / or using a more “intelligent” (and possibly semantic) web in bioinformatics.


A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies, Nat Biotech

The paper described a framework for comparisons across gene expression microarray platforms and laboratories, which including: 1) Affymetrix; 2) Agilent; 3) Applied Biosystems (ABI); 4) Amersham (now GE Healthcare); 5) cDNA arrays provided by the Cepko laboratory (academic cDNA); 6) Compugen (now Sigma-Genosys); 7) Mergen; 8) long oligonuceotide arrays from the Microarray Core facility at Massachusetts General Hospital (MGH long oligo); 9) MWG BioTech (now Ocimum Biosolutions); 10) Operon. As a result, the commercial platform ABI has the best performace, where the academic cDNA from Harvard poorest.