archives

Date

Chembank

MIT, Harvard and Broad alliance has released Chembank 2.0 [ http://chembank.broad.harvard.edu/ ], a repo of small molecules. Looks interesting but has the glitch of 'register b4 use'.


Machine Learning for better Clinical Gene Expression Signatures

Machine Learning Algorithms
for Clinical and Research Microarray Data Analysis

Mining Microarray Data to Discover:

Disease Biomarkers & Complex Genetic Relationships

Biomind LLC WHITE PAPER

January 2006

Molecular biomarkers associated with disease and disease predisposition may be used for diagnostic purposes in the early detection and characterization of various disorders. Microarray and SNP data have been used extensively based upon their respectively high resolution of gene expression and polymorphism. And, while diagnostic, pharmacogenomic, and research uses for such biomarkers have proliferated, methods for their identification have standardized. Biomind has developed software which sifts through large, complex microarray datasets to accurately identify biomarkers implicit in clinical disease data. The software uses machine learning algorithms which integrate the Gene Ontology (GO) and Protein Information Resource (PIR).


BioGrids

From Tim Bray to Jim Gray (via Seymour Cray)

Recycle or Globus Toolkit?
Grid Computing already plays an important role in the life sciences, and will probably continue doing so for the forseeable future. BioGrid (Japan), myGrid (UK) and CoreGrid (Europe) are just three current examples, there are many more Grid and Super Duper Computer projects in the life sciences. So, is there an accessible Hitch Hikers Guide to the Grid for newbies, especially bioinformaticians?


Dub Dub Dub '06

The 15th International World Wide Web conference is currently underway in Edinburgh, Bonny Scotland. As usual, this popular conference has some good papers, only 11%* of submissions are accepted. One particular paper caught my eye:


Before leaving to a conference

What do you do before leaving for a conference in another (OECD) country? I have some geekish ideas, but could need more: Have a look at Craig's list to see what to do after the conference is finished, download a hotspot locator (The first one I found was Jiwire), check out TripAdvisor, get a calling card and a telephone cable to use your modem if there are not enough hotspots. Maybe buy a thing like a Lonely Planet. Download some papers to read on the airplane. Unfortunately google earth is not usable offline. Any other ideas?


Nodalpoint in Technorati?

I was wondering, are there any plans to add nodal point to blog search engines like Technorati?. From their marketing hype, it seems like a good idea. However, if this isn't a good idea, what are the reasons?


Postgenomic greasemonkey script

I posted a small greasemonkey test script in the wiki to add links to postgenomic into journal webpages. It is more a proof of principle since I was learning how to to do Gresemonkey scripts with this as an example. The idea is simple, go through the webpage in search of a DOI and if this DOI is listed in Postgenomic it adds a link and a small picture next to the DOI to link back to postgenomic. This way when you are browsing the journal you know if someone has talked about it in some blog.


Source Code for Biology and Medicine

(Via chem-bla-ics and Yakafon)

BioMed Central will be hosting a new journal entitled "Source Code for Biology and Medicine". According to journal description:
Source Code for Biology and Medicine aims to publish source code for distribution and use in the public domain in order to advance biological and medical research. Through this dissemination, it may be possible to shorten the time required for solving certain computational problems for which there is limited source code availability or resources.


Technology in the news

Over at my little blog, I've been musing on how articles about web technology are entering the mainstream media. Examples include a recent SMH story on mash-ups (warning: fairly awful) and in the Guardian technology blog, a small piece on Google Trends.

Google Trends is quite addictive and informative. Try "bioinformatics" as a query - the trend for the past 2 years is rather interesting.


BioInformatics Support and Analysis

Welcome to BISA (BioInformatics Support and Analysis) hhtp://www.bisa.in
a novice concept to help, aware and assist scientific community in and about the field of bioinformatics.

As Bioinformatics has become an integral part of biological studies, there is a need for introducing an explicit protocol-based approach to Bioinformatics analysis. The objective of BISA is to make it practical for life scientists to design and execute reusable dry-lab protocols. BISA presents a service named "Rweb" that can browse the web and extract the data to complete data collection and subsequent analysis task or independent tasks as such. BISA presents Rweb an online resource management system. Powered with ORiMS and PAS.