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Who can find a paper of the month?

I was skimming through my RSS feeds in search of a "paper of the month" and I came up short. It was rather disheartening actually - a lot of current publications in bioinformatics seem to consist of:

  • new algorithms without practical application
  • findings of low general interest by beginners using the most basic of tools e.g. BLAST
  • badly designed database frontends with no functionality

I'm beginning to worry that bioinformatics is in danger of failing to live up to its promises. We have to convince the unenlightened that our tools, applied intelligently, can provide meaningful insight into real biological problems of fundamental interest. Yet I see little evidence of this at the moment.
Could someone please find a really good paper or suggest a fantastic collaborative project, or I'll get really depressed.